VPAC Receptor Agonism & Neuroimmune Modulation. Research-grade protocols, administration guidelines, and safety considerations.
Research Use Only. The information on this page is intended for educational and research purposes only. VIP is not approved for human therapeutic use. Consult a qualified healthcare professional before use.
VIP is a 28-amino-acid neuropeptide that acts as an agonist at VPAC1 and VPAC2 receptors (vasoactive intestinal peptide receptors). It has potent vasodilatory, anti-inflammatory, and immunomodulatory effects. VIP inhibits pro-inflammatory cytokine production (TNF-alpha, IL-6, IL-12) and promotes regulatory T-cell activity.
| Protocol | Dose | Frequency | Route | Duration |
|---|---|---|---|---|
| Immune/Anti-Inflammatory Research | 50 mcg | Once or twice daily | SubQ or intranasal | 4–8 weeks |
| Pulmonary Research | 50–100 mcg | Twice daily | Intranasal | 4–6 weeks |
| Conservative Start | 25 mcg | Once daily | SubQ injection | 2–4 weeks |
Research protocols typically use 50 mcg administered subcutaneously or intranasally once or twice daily. Intranasal delivery is commonly used in CIRS (Chronic Inflammatory Response Syndrome) research protocols.
VIP can be administered subcutaneously (injection) or intranasally. Intranasal delivery is preferred in some protocols for direct CNS access and convenience.
Research cycles typically run 4–8 weeks. VIP is often used as part of a broader treatment protocol in CIRS research.
Injectable VIP requires reconstitution with bacteriostatic water. Intranasal VIP formulations are typically pre-mixed solutions.
Research has shown VIP has potent anti-inflammatory effects, regulates immune cell activity, improves pulmonary function, and modulates circadian rhythms. It is studied in CIRS, autoimmune conditions, and pulmonary hypertension.
≥99% purity, third-party tested, Certificate of Analysis available. Ships with BAC water included.
Shop VIP at Purgo LabsMedical Disclaimer: All content on this site is for educational and research purposes only. Research peptides are not FDA-approved for human use. Always consult a qualified healthcare professional before considering any peptide or supplement protocol. Nothing on this site constitutes medical advice, diagnosis, or treatment.