Cardiolipin Stabilization & Mitochondrial Membrane Protection. Research-grade protocols, administration guidelines, and safety considerations.
Research Use Only. The information on this page is intended for educational and research purposes only. SS-31 is not approved for human therapeutic use. Consult a qualified healthcare professional before use.
SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide that selectively concentrates in the inner mitochondrial membrane. It binds to cardiolipin — a phospholipid critical for cristae structure and electron transport chain function — stabilizing it and reducing reactive oxygen species (ROS) production.
| Protocol | Dose | Frequency | Route | Duration |
|---|---|---|---|---|
| Mitochondrial Research | 5 mg | Once daily | SubQ injection | 8–12 weeks |
| Cardiovascular Research | 10 mg | Once daily | SubQ injection | 6–8 weeks |
| Conservative Start | 2.5 mg | Once daily | SubQ injection | 4–6 weeks |
Research protocols typically use 5–10 mg administered subcutaneously once daily. Lower doses of 2.5 mg are used in conservative starting protocols.
SS-31 is typically administered in the morning in research protocols. Some cardiovascular research protocols administer it before exercise.
Research cycles typically run 8–12 weeks. SS-31 is often used in longer protocols given its mitochondrial protective mechanism.
Yes. SS-31 is supplied as a lyophilized powder and must be reconstituted with bacteriostatic water before injection.
Research has shown SS-31 stabilizes cardiolipin in the inner mitochondrial membrane, reduces oxidative stress, improves mitochondrial function, and has shown cardioprotective effects in multiple animal models.
≥99% purity, third-party tested, Certificate of Analysis available. Ships with BAC water included.
Shop SS-31 at Purgo LabsMedical Disclaimer: All content on this site is for educational and research purposes only. Research peptides are not FDA-approved for human use. Always consult a qualified healthcare professional before considering any peptide or supplement protocol. Nothing on this site constitutes medical advice, diagnosis, or treatment.