The Definitive Peptide Research Reference Guide — Compound Review

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GHRP Peptides Research Hub

Growth Hormone Releasing Peptides (GHRPs) stimulate GH release via the ghrelin receptor — a complementary pathway to GHRH analogues. This hub covers Ipamorelin, GHRP-2, and GHRP-6.

What Are GHRP Peptides?

Growth Hormone Releasing Peptides (GHRPs) are a class of synthetic peptides that stimulate pituitary GH secretion by binding to the GHS-R1a receptor — the same receptor activated by the endogenous hormone ghrelin.

The Three Primary GHRPs

Ipamorelin: most selective, minimal cortisol/prolactin elevation, preferred for research. GHRP-2: moderate selectivity, stronger GH pulse, some cortisol elevation. GHRP-6: least selective, significant appetite stimulation via ghrelin mimicry.

Head-to-Head Comparison

Selectivity, cortisol impact, prolactin elevation, appetite stimulation, and research applications compared across all three primary GHRP compounds — with stacking rationale for each.