Tirzepatide titration schedule: SURPASS trial-based dose escalation protocol for research applications.
Standard SURMOUNT Titration Schedule (6 Phases)
Week-by-week dose escalation protocol based on SURMOUNT-1 trial data — from 2.5 mg to 15 mg/week
Standard vs Slow Titration: Which Is Right?
The following table reflects the exact titration schedule used in SURMOUNT-1 and SURMOUNT-2 trials. Each phase lasts 4 weeks. Weight loss percentages at each dose level are derived from SURMOUNT-1 interim data at the corresponding time points.
SURMOUNT-1 Dose-Response at 72 Weeks
Week-by-week dose escalation protocol based on SURMOUNT-1 trial data — from 2.5 mg to 15 mg/week