Semaglutide vs Wegovy: they are the same molecule. Wegovy is the brand name for semaglutide approved for chronic weight management at 2.4 mg/week. Ozempic is semaglutide approved for T2D at up to 2 mg/week.
Same Molecule, Different Indication
Semaglutide is the active ingredient in both Ozempic and Wegovy. The difference is the approved indication and maximum dose: Wegovy (2.4 mg/week) for obesity, Ozempic (2 mg/week) for T2D.
Dose Difference Impact
The additional 0.4 mg in the Wegovy dose produces approximately 2–3% additional weight loss compared to the 2 mg Ozempic dose in clinical studies. The titration schedule is also longer for Wegovy (16 weeks vs 12 weeks for Ozempic).
Research-Grade Semaglutide
Research-grade semaglutide is the same molecule as both Ozempic and Wegovy, available for laboratory research. The dose used in research protocols typically mirrors the Wegovy titration schedule for weight loss research.