CJC-1295 + Ipamorelin combination protocol: the most commonly researched GHRH + GHRP stack, combining sustained GH axis stimulation with selective GH pulse amplification.
Combination Dosage Protocol
CJC-1295 (no DAC / Mod GRF 1-29): 100–200 mcg + Ipamorelin: 200–300 mcg, injected simultaneously 2–3x daily. The combination produces synergistic GH release greater than either compound alone.
Why This Stack Works
CJC-1295 acts on GHRH receptors to prime the pituitary for GH release. Ipamorelin acts on ghrelin receptors (GHS-R1a) to amplify the GH pulse. The dual-receptor mechanism produces 2–5x greater GH release than either compound alone.
Timing Protocol
Most research protocols use: morning injection upon waking (fasted), pre-workout injection, and evening injection before sleep. The pre-sleep injection is considered most important as it amplifies the natural nocturnal GH pulse.